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(Gly22)-Amyloid β-Protein (1-40)
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(Gly22)-Amyloid β-Protein (1-40) 
编号: DC160031(31)
CSA号: 175010-18-1
产品详情

(Gly22)-Amyloid β-Protein (1-40)

CompanySerial NumberDC160031(31)

ProductName(Gly22)-Amyloid β-Protein(1-40)

Synonym Amyloidβ-Protein (1-40) Arctic Mutation, Amyloid β-Protein (1-40) E22G

CASNo.[175010-18-1] net

Sequence(three-letter)H-Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Gly-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-OHTrifluoroacetate salt

Sequence(one-letter) DAEFRHDSGYEVHHQKLVFFAGDVGSNKGAIIGLMVGGVV-OHTrifluoroacetatesalt

ConstitutionalFormula

MolecularFormula C191H291N53O56S

MolecularWeight

References A.P?ivi?et al., J. Mol. Biol., 339, 145 (2004)
B.M.Whalen et al., Neurobiol. Dis., 20, 254 (2005)
N.Yamamoto et al., J. Biol. Chem., 282, 2646 (2007)
A.R.Lam et al., J. Am. Chem. Soc., 130, 17413 (2008)
R.Solito et al., Exp. Cell Res., 315, 385 (2009)
A.Jan et al., Nat. Protoc., 5, 1186 (2010)

IllustrationThehighly neurotoxic arctic mutant (E22G) of Aβ has been used to study themechanisms underlying the formation of soluble and insoluble β-amyloidaggregates. As the wild-type Aβ, the arctic mutant preferably assembles in thepresence of GM1 ganglioside.

ConditionOf Storage: -20± 5 °C

本产品仅供研发使用,不能用于人体


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