Amyloid β/A4 Protein Precursor770 (135-155)

CompanySerial Number：DC160002

ProductName：Amyloid β/A4 ProteinPrecursor770 (135-155)

Synonym： APP770(135-155)

CASNo.：[315229-44-8]

Sequence(three-letter)：H-Phe-Leu-His-Gln-Glu-Arg-Met-Asp-Val-Cys-Glu-Thr-His-Leu-His-Trp-His-Thr-Val-Ala-Lys-OH

Sequence(one-letter)： FLHQERMDVCETHLHWHTVAK-OH

ConstitutionalFormula：

MolecularFormula： C116H173N35O31S2

MolecularWeight：2618

References： G.Multhaupet al., Science, 271, 1406 (1996)

Illustration：ThisAPP fragment comprises a copper(II)-binding site. Binding of Cu(II) to thepeptide induced oxidation of the cysteine and intermolecular dimerization ofthe peptide. The reduction of Cu(II) to Cu(I) by APP may enhance the productionof hydroxyl radicals which in turn may contribute to neurodegeneration inAlzheimer's disease.

ConditionOf Storage: -20± 5 °C

★ 本产品仅供研发使用，不能用于人体